Principal Investigator


Principal Investigator

Catherine J. Chu, MD, MMSc, MA

Dr. Chu is a board-certified child neurologist, epileptologist, and neurophysiologist at Massachusetts General Hospital and Associate Professor of Neurology at Harvard Medical School.  She received her BS in neurobiology and behavior from the University of Washington, MD and MMSc from Harvard Medical School, and MA in social anthropology from Harvard University. Clinically, Dr. Chu is the director of neonatal and pediatric EEG monitoring and director of the pediatric responsive neurostimulation clinic at MGH. Clinically, Dr. Chu specializes in EEG analysis, seizure localization, surgical planning, and neuromodulation for patients with difficult to control epilepsy. Dr Chu’s research focuses on identifying and understanding how brain rhythms contribute to seizures and cognitive symptoms in epilepsy using invasive and noninvasive multimodal imaging. Actively funded projects in the Chu Lab include studies on thalamocortical circuit dysfunction in sleep-activated epilepsy, translational studies evaluating spike ripples as a biomarker in epilepsy, testing improved approaches of neuromodulation in cortical epilepsy, and understanding the relationship between hippocampal rhythms and sleep-dependent memory function. She is also active in several multicenter collaborative networks to improve our understanding of neonatal seizures and early life epilepsies. Outside of work, Dr. Chu is the proud mom to 3 awesome kids and enjoys tackling endless home improvement projects with her husband. [Link to CV]

Lab Members

Wen received her PhD degree in Electrical Engineering from Nanyang Technological University, Singapore in 2015 and Bachelor of Engineering degree in Computer Science from Jinan University, P. R. China in 2011. Wen has worked on various types of analysis of biomedical signals including ECG, EEG, PSG, MRI, and acoustic signals. She is interested in building automated analytic models by developing predictive, actionable algorithms for better performance and efficiency. In the Chu Lab, Wen is developing tools to detect and analyze spike ripples as an improved biomarker for the epileptogenic cortex compared to either spikes or ripples alone.




Grace Xiao, BS
Medical School Student Research Assistant

Grace Xiao is a medical school student at Johns Hopkins. Previously, she did her undergraduate work at Harvard studying neurobiology and economics. She is interested in creating impact through research, policy and entrepreneurship. In the Chu lab, Grace assisted with collecting and analyzing neuroimaging data for the Rolandic epilepsy project and completed an Honors thesis evaluating spike morphological differences and seizure risk in epilepsy. 


Anvitha Sathya
Medical School Student Research Assistant

Anvitha is currently a fourth year student in Boston University’s Seven Year BA/MD program with a minor in English and an interest in neurological patient care. She has previously worked in labs studying neuromuscular diseases and neurological injuries. Anvitha helps with multimodal imaging and experimental data collection in children for the Rolandic epilepsy project and performs electrode localizations for projects using invasive EEG data.

John McLaren, MD
Pediatric Epilepsy Fellow

John is currently an Epilepsy Neurology fellow at Massachusetts General Hospital. He completed his undergraduate degree at Boston College, majoring in Music and Neuroscience, his Medical Doctorate at the University of Vermont College of Medicine, and his Child Neurology residency at MGH. After completing his Neurology training, he will be staying on at MGH as an Epilepsy fellow. His research interest is in diagnostics and therapeutics for children with epileptic encephalopathies.

Yancheng Luo, MD
Junior Faculty

YC (Yancheng) Luo is a graduate of the Child Neurology fellowship at Massachusetts General Hospital and current junior faculty at Boys Town National Research Hospital in Omaha, Nebraska.  During his childhood neurology residency at MGH, he started working with Dr. Chu on electrophysiology data analysis and he hopes to continue this research interest in his career.


Summer Uhrich
Undergraduate Student Research Assistant

Summer is currently a student at Boston College majoring in Neuroscience with an interest in Behavioral Neuroscience. As an intern in the Chu Lab, she will help perform automated spike detection on multicenter intracranial EEG datasets and assist with cognitive tasks and MEG/EEG/MRI data collection on subjects in the research setting.

Tai Chu-Shore






Mark Kramer, PhD
Professor of Math and Statistics, Boston University
Matti Hamalainen, PhD
Professor of Radiology,  Harvard Medical School
Uri Eden, PhD 
Professor of Math and Statistics, Boston University
Dara Manoach, PhD 
Professor of Psychology, MGH, Harvard Medical School
Xue Han, PhD
Associate Professor of Biomedical Engineering, Harvard Medical School
Britt Carlson Emerton, PhD
Instructor of Psychology, MGH, Harvard Medical School
Brandon Westover, MD, PhD
Associate Professor of Neurology, MGH, Harvard Medical School
Mark Richardson, MD, PhD
Associate Professor of Neurology, MGH, Harvard Medical School
Ona Wu, PhD
Associate Professor, Radiology, Harvard Medical School



Research Consortiums


Center for Neurotechnology and Recovery

Neonatal Seizure Registry

Pediatric Epilepsy Research Consortium

Division of Sleep Medicine

Massachusetts General Neuroscience



Former Lab Members

lab position / post-lab position

Elizabeth Spencer, PhD (graduate student in mathematics and statistics, Boston University / post-doc at Carnegie Mellon University)

Lauren Ostrowski, BS (honors undergraduate student in neuroscience, Brown University / MD, PhD Candidate, MSTP, University of California San Diego)

Grace Xiao, MD (honors undergraduate student in neuroscience, Harvard University / MD Candidate, Johns Hopkins Medical School)

Anehita Oribabor, MEng (clinical research coordinator / industry)

Sally Stoyell, BS (research coordinator / Psychology PhD Candidate, University of Minnesota)

Dan Song, BSE (research coordinator / Biomedical Engineering PhD Candidate, Northwestern University)

Emily Thorn, BS, MA (research coordinator, graduate student in neuroscience, Boston University / MD Candidate, Washington State University Medical Center)

Lila Worden, MD (pediatric neurology resident researcher / Children’s Hospital of Philadelphia epilepsy fellowship)

Erin Ross, BS (co-op student, Northeastern University, research coordinator / MD Candidate, UC Southern California Medical School)

McKenna Parnes, MSEd, PhD (graduate student in psychology / psychology residency, Brown University)

Wenting Xie, BS (clinical research coordinator / computer science MS candidate, Cornell University)

Rebecca Weiss, BS (clinical research coordinator / MGH neonatology clinical research coordinator)

Kyla Cordrey, BS (honors undergraduate student in neuroscience, Harvard University / MD Candidate, Johns Hopkins Medical School)

Katica Boric, PhD, MSc (clinical research coordinator / Decision Lab Manager, Spain)

Juan Diaz, BS (clinical research coordinator / MBA candidate, Dartmouth University)

Rayna Trietsch, BS (clinical research coordinator / MD candidate, Tufts University Medical School)

Jennifer Leahy, BS (clinical research coordinator / Psychology PhD candidate, University ofMassachusetts)

Stefania Sokolowski (honors undergraduate student in neuroscience, Boston University / strategic analyst, Memorial Sloan Kettering Cancer Center)